***Chairman & Associate Professor of Molecular Genetics***Member, IRMC Council, Institute for Research and Medical Consultations***Formerly Team Representative, Dept. of Genetic Research, IRMC, Imam Abdulrahman Bin Faisal University (Formerly: University Of Dammam), KSA*** ***Formerly Academic Sub. Committee Convener, International Indian School Dammam*** ***Formerly Deputy Chairman, International Indian School Dammam, Dammam, KSA ***
About Me
- Dr. J. Francis Borgio
- Dammam, India
- Dr. J. Francis Borgio is an Associate Professor of Molecular Genetics in the Department of Genetic Research at the Institute for Research and Medical Consultations (IRMC), University of Dammam, Saudi Arabia. He is a member of IRMC Main Council, University of Dammam. He was a Deputy Chairman and a member of managing committee, International Indian School Dammam (IISD), one of the biggest school in the Gulf with 18,000 students. He received his Ph.D. in Microbiology from MS University, Tamil Nadu, India. He is having 12 years of experience in the field of Molecular Genetics, and Hemoglobinopathies. He is an author of a book and more than 75 research papers in high impact journals. He reviewed over 250 research articles for various journals including Blood Reviews and Clinical Genetics. He is a Principle Investigator many major funded research projects. He was trained as a molecular biologist at NBRI, CSIR, Lucknow and Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bangalore, India. He has been an external Ph.D examiner for various Universities, including Anna University, Chennai, India. He is a recipient of various Fellowships, Grants and Awards.
His Royal Highness Prince Saud Bin Nayef Al Saud, Governor of the Eastern Province& J Francis Borgio
His Royal Highness the Governor of the Eastern Province, & His Excellency the President of the IAU
Dr. J. Francis Borgio with His Excellency The President of University of Dammam.
Dr J Francis Borgio felicitates His Excellency the Indian Deputy Chief of Mission at IISD
Hajee M.J. Jamal Mohamed (TREASURER, JMC Trichy) felicitates J Francis Borgio
Chief Guest and delivers Inaugural Address
IISD Managing Committee with Director of the Foreign Edu. and HE DCM
4th Annual Poster Day (IRMC-SRP-2022) of IRMC
IAU-College of Medicine Research & Innovation day
At the top of Europe, Jungfraujoch, Switzerland
With The Vice President of KACST, President of IAU, Vice President of IAU, Dean of IRMC
3rd Annual Poster Day (IRMC-SRP-2021) of IRMC
At the PhD Viva Voce of my 1st PhD Student, Dr AlHur
At Vatican Museums Rome
6th HEALTH PROFESSIONS CONFERENCE 2022, at King Saud Bin Abdulaziz University for Health Sciences
St. Peter's Basilica, Vatican City, Rome
St. Peter's Basilica, Vatican City, Rome
Rev. Fr. Antonysamy (St Xavier's College, Palayamkottai) felicitates Dr Francis Borgio
Dr J Francis Borgio Receives Guest of Honor from The Director, Venus International Foundation
IISD Foundation Day 2015
With His Excellency, Mr. Ahmad Javed Ambassador of India to Saudi Arabia
Dr J Francis Borgio felicitates His Excellency, Mr. A Javed Ambassador of India to Saudi Arabia
Focus Dammam, Independence Day 15th Aug 2016 at LuLu Khobar
With His Excellency, Mr. Ahmad Javed Ambassador of India to Saudi Arabia
Republic Day 2017
At the top of Europe, Jungfraujoch, Switzerland
Borgio with His Excellency, Mr. Ahmad Javed Ambassador of India to Saudi Arabia
Funded Research Projects Completed
- Principal Investigator 2015-2016 Development of simple PCR method for the detection of newly discovered α12 allele as part of premarital screening KACST, Saudi Arabia. (INR : 25,08,500)
- Principal Investigator 2013-2015 Sequence variants of the AHSP gene in Saudi subjects with α-thalassemia and/or β-thalassemia mutations DSR, UoD, Dammam, KSA. (INR : 32,85,500) [$ 53,294]
- Co-PI 2012-2014 Studies on genetic variants of 9p21 and 10p11.23 loci in the development of coronary artery disease in population of the Eastern Province of Saudi Arabia DSR, UoD, Saudi Arabia. (INR : 32,77,500) [$ 53,294]
- Co-PI 2014-2016 Microarray gene profiling of sickle cell disease with cardiovascular complications DSR, UoD, KSA. (INR : 32,77,500) [$ 53,294]
- Co-PI: 2012-2014 Genetic variants of 9p21 and 10p11 loci in CVD patients DSR, UoD, Saudi Arabia. 199,900 SAR (INR : 32,77,500)
- PI: 2012-2014: Gene polymorphisms and dental caries among children DSR, UoD, Saudi Arabia. 199,000 SAR (INR : 32,80,000)
- Co-PI: 2012-2014: Molecular nature of point α globin defects in Saudis DSR, UoD, KSA. 199,800 SAR (INR : 32,76,000)
- Co-PI: 2013-2014: ATRX gene defects in healthy Saudi population. DSR, UoD, KSA. 100,000 SAR (INR : 16,20,000)
- PI: 2011-2013: Development of simple multiplex PCR assay to detect the prevalent bacterial and fungal infections. KACST, Saudi Arabia. 112,000 SR (INR : 17,92,000)
- PI: 2011-2012: Screening of carriers for ATRX syndrome in alpha thalassemia patients . DSR, University of Dammam, Saudi Arabia. 96,000.00 SR (INR: 14,00,000)
At University of Verona, Verona, Italy
At St. Mark's Square, Venice, Italy
At The Spire of Dublin, Ireland
At Ponte del Prefetto o Papadopoli: a bridge in Venice, Italy
At Ponte del Prefetto o Papadopoli: a bridge in Venice, Italy
Borgio receives SEED MONEY GRANT AWARD from Honorable Director, IISc., Prof. Balaram. on 29.09.10
State Award Function by Govt. of Karnataka.
At Jawaharlal Nehru Centre for Advanced Scientific Research(JNCASR)
St. Peter's Basilica, Vatican City, Rome
2024 Publications
- Molecular Informatics in Precision Medicine
- Genome-Guided Identification of Surfactin-Producing Bacillus halotolerans AQ11M9 with Anti-Candida auris Potential
- Phenomics and genomic features of Enterococcus avium IRMC1622a isolated from a clinical sample of hospitalized patient
- The Potential of Dutasteride for Treating Multidrug-Resistant Candida auris Infection
- Abstracts of “Institute for Research and Medical Consultations (IRMC) - Summer Research Program - 2023” presented at Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia, on August 28, 2023
- Method for early determination of gender by multiplex pcr detecting four genes
- Silver silicalite zeolite nanomaterials for reducing candida auris biofilms
2023 Publications
- Heterogeneity in biomarkers, mitogenome and genetic disorders of the Arab population with special emphasis on large-scale whole-exome sequencing
- Mining the nanotube-forming Bacillus amyloliquefaciens MR14M3 Genome for Determining anti-Candida auris and anti-Candida albicans Potential by Pathogenicity and Comparative Genomics Analysis
- Genomic Insights into Virulence Factors and Multi-Drug Resistance in Clostridium perfringens IRMC2505A
- Exome-wide analysis identify multiple variations in olfactory receptor genes (OR12D2 and OR5V1) associated with autism spectrum disorder in Saudi females
- The Effectiveness of Nigella sativa and Ginger as Appetite Suppressants: An Experimental Study on Healthy Wistar Rats
- Abstracts of “Institute for Research and Medical Consultations (IRMC) - Summer Research Program - 2022” presented at Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia, on September 14, 2022
- Isolation, Screening, and Identification of Alkaline Protease-Producing Bacteria and Application of the Most Potent Enzyme from Bacillus sp. Mar64
- Genomic Landscape of Multidrug Resistance and Virulence in Enterococcus faecalis IRMC827A from a Long-Term Patient
- Filaggrin gene variants among Saudi patients with ichthyosis vulgaris
- Entomopathogenic fungi and their biological control of Tetranychus urticae: Two-spotted spider mites
2022 Publications
- Integration of Transcriptome and Exome Genotyping Identifies Significant Variants with Autism Spectrum Disorder
- Novel Feather Degrading Keratinases from Bacillus cereus Group: Biochemical, Genetic and Bioinformatics Analysis
- The association between two genetic polymorphisms in ITGB3 and increase risk of venous thromboembolism in cancer patients in Eastern Province of Saudi Arabia
- Exome array identifies functional exonic biomarkers for pediatric dental caries
- Therapeutic Intervention for Various Hospital Setting Strains of Biofilm Forming Candida auris with Multiple Drug Resistance Mutations Using Nanomaterial Ag-Silicalite-1 Zeolite
- Celomic Fluid: Laboratory Workflow for Prenatal Diagnosis of Monogenic Diseases
- Safety of Tocilizumab in COVID-19 Patients and Benefit of Single-Dose: The Largest Retrospective Observational Study
- A Pilot Mitochondrial Genome-Wide Association on Migraine Among Saudi Arabians
- Genotoxicity Evaluation of Pectin-Mediated Gold Nanoparticles on Zebrafish Embryos (Danio rerio)
- Study of Single Nucleotide Polymorphisms Associated with Breast Cancer Patients among Arab Ancestries
- Phenotypic and Genotypic Signatures of VWF Exon 18 in Eastern Saudi Patients Previously Diagnosed with Type 1 von Willebrand Disease
- Whole-Exome Sequencing Reveals Migraine-Associated Novel Functional Variants in Arab Ancestry Females: A Pilot Study
2021 Publications
- Whole-Genome Sequencing Reveals Exonic Variation of ASIC5 Gene Results in Recurrent Pregnancy Loss
- Emerging Status of Multidrug-Resistant Bacteria and Fungi in the Arabian Peninsula
- Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine
- Drug Resistance-Associated Mutations in ERG11 of Multidrug-Resistant Candida auris in a Tertiary Care Hospital of Eastern Saudi Arabia
- Genome composition and genetic characterization of SARS-CoV-2
- Functional multigenic variations associated with hodgkin lymphoma
- Deleterious missense variants in the aflatoxin biosynthesis genes explain the low toxicity of Aspergillus flavus from infected rice
- Association between sex hormones and migraine in young Saudi females
- Exome array identifies functional exonic biomarkers for pediatric dental caries
- Identification and Antibacterial Characterization of Endophytic Fungi from Artemisia sieberi
- Haemoglobin switching modulator SNPs rs5006884 is associated with increased HbA 2 in β-thalassaemia carriers
- Diagnostic Accuracy of Serum Calcitonin Gene-Related Peptide and Apolipoprotein E in Migraine: A Preliminary Study
- Predominance of non-Streptococcus mutans bacteria in dental biofilm and its relation to caries progression
- The association between two genetic polymorphisms in ITGB3 and increase risk of venous thromboembolism in cancer patients in Eastern Province of Saudi Arabia
- 2020
- Risk Y-haplotypes and pathogenic variants of Arab-ancestry boys with autism by an exome-wide association study
- Antibacterial potentials of methanolic extract and silver nanoparticles from marine algae
- State-of-the-art tools unveil potent drug targets amongst clinically approved drugs to inhibit helicase in SARS-CoV-2
- Co-inheritance of alpha globin gene deletion lowering serum iron level in female beta thalassemia patients
- Abstracts of "Institute for Research and Medical Consultations (IRMC) - Summer Research Program for Undergraduate Students – 2019" presented at Imam Abdulrahman Bin Faisal University
- State-of-the-art tools to identify druggable protein ligand of SARS-CoV-2
- Direct electricity production from Microalgae Choricystis sp. and investigation of the boron to enhance the electrogenic activity
- High Prevalence of Aflatoxin B1 in Aspergillus flavus Infecting Stored Rice Grains
- Antimicrobial effect of Sargassum plagiophyllum mediated gold nanoparticles on Escherichia coli and Salmonella typhi
- Molecular, physiological, and biochemical characterization of extracellular lipase production by Aspergillus niger using submerged fermentation
- Antibacterial potentials of methanolic extract and silver nanoparticles from marine algae
- 2019
- Genetic Disorder Prenatal Diagnosis and Pregnancy Termination Practices Among High Consanguinity Population, Saudi Arabia
- Functional DNA Variations Associated With Saudi Female With Low VO 2max: A Pilot Microarray Study
- Co-inheritance of Alpha Globin Gene Deletion Lowering Serum Iron Level in Female Beta Thalassemia Patients
- Novel Haplotype Indicator for End-Stage Renal Disease Progression Among Saudi Patients
- The rs61742690 (S783N) single nucleotide polymorphism is a suitable target for disrupting BCL11A-mediated foetal-to-adult globin switching.
- Isolation and Characterization of a Novel Thermophile; Bacillus haynesii, Applied for the Green Synthesis of ZnO Nanoparticles
- Cisplatin-functionalized Three-Dimensional Magnetic SBA-16 for Treating Breast Cancer Cells (MCF-7)
- SPIONs/3D SiSBA-16 Based Multifunctional Nanoformulation for Target Specific Cisplatin Release in Colon and Cervical Cancer Cell Lines
- Environmental and Genetic Factors in Autism Spectrum Disorders: Special Emphasis on Data from Arabian Studies
- Identification of seven novel variants in the β-globin gene in transfusion-dependent and normal patients
- 2018
- A comprehensive review of the prevalence of beta globin gene variations and the co-inheritance of related gene variants in Saudi Arabians with beta-thalassemia.
- Highly deleterious variations in COX1, CYTB, SCG5, FK2, PRL and PGF genes are the potential adaptation of the immigrated African ostrich population.
- Hemoglobin A2 (HbA2) has a measure of unreliability in diagnosing β-thalassemia trait (β-TT).
- Optimal pcr primers for rapid and accurate detection of Aspergillus flavus isolates.
- KLF1 gene and borderline hemoglobin A2 in Saudi population.
- The ‑α3.7 deletion in α‑globin genes increases the concentration of fetal hemoglobin and hemoglobin A2 in a Saudi Arabian population
- 2017
- Impact of annotation error in α-globin genes on molecular diagnosis
- Type 2 diabetes associated variants of KCNQ1 strongly confer the risk of cardiovascular disease among the Saudi Arabian population
- Existence of HbF Enhancer Haplotypes at HBS1L-MYB Intergenic Region in Transfusion-Dependent Saudi β-Thalassemia Patients
- Association of MBL2 gene polymorphism with the dental caries in Saudi children. Caries Research 51(1):12-16. Impact factor: 2.278.
- 2016
- Mutation near the binding interfaces at α-hemoglobin stabilizing protein is highly pathogenic. American Journal of Translational Research. 8(10):4224-4232. Impact factor: 3.402.
- Association of SNP rs2487928 on chromosome 10p11.2 with the risk of coronary artery disease based myocardial infarction in a Saudi population. International Journal of Clinical and Experimental Pathology. 9(5): 5628-5634. Impact factor: 1.891.
- Intronic polymorphisms in CDKN2B-AS1 gene are strongly associated with the risk of myocardial infarction and coronary artery disease in the Saudi population. International Journal of Molecular Sciences. 17(3), 395; doi:10.3390/ijms17030395. Impact factor: 3.254.
- In-silico computing of the most deleterious nsSNPs in HBA1 gene. PLoS ONE 11(1): e0147702. doi:10.1371/journal.pone.0147702. Impact factor: 3.234.
- Mutations in the β-globin gene from a Saudi population: An update. International Journal of Laboratory Hematology 38(2):e38-e40. Impact factor: 1.819.
- 2015
- Molecular nature of alpha-globin genes in the Saudi population. Saudi Medical Journal. 36(11): 1271-1276. Impact factor: 0.588.
- Co-inheritance of novel ATRX gene mutation and globin (α & β) gene mutations in transfusion dependent beta-thalassemia patients. Blood Cells, Molecules and Diseases. 55(1): 27-29. Impact factor: 2.65.
- 2014
- A novel HBA2 gene conversion in cis or trans: "α12 allele" in a Saudi population. Blood Cells, Molecules and Diseases. 53(4): 199-203. PMID: 25065854. Impact factor: 2.65.
- Route of infection and haematological effect of Metarhizium anisopliae (Metsch.) Sorokin on Dysdercus cingulatus (Fab.) adult. Journal of Basic Microbiology. 54(1):6-17. doi: 10.1002/jobm.201200258. PMID: 23456609. Impact factor: 1.82.
- 2013
- Spectrum of α-thalassemia mutations in transfusion dependent β-thalassemia patients from the Eastern Province of Saudi Arabia. Hemoglobin 2013,37(1): 65–73. PMID: 23297837
- 2012
- EntomoBrasilis 2012
- Journal of Entomology...2012
- 2011
- American Journal of Biochemistry and Molecular Biology
- RNA interference ... Journal of Biosciences ... 2011
- American Journal of Drug Discovery
- Research & Reviews: A Journal of Microbiology & Virology ...2011
- 2010
- Virulence of Entomopathogenic Fungus Metarhizium ....2010
- RNAi mediated gene knockdown..... 2010
- Is the failure of expression ........due to qiRNA? 2010
- 2009
- Gene Silencing for medicinal plant research JMPR Dec 2009
- African Journal of Biotechnology 8 (20), 19 October 2009
- Journal of Plant Protection Research. 2009. 49: 2.
- Archives Of Phytopathology And Plant Protection
- 2008
- Internet Journal of Microbiology 2008 Volume 5: 2
- Ethnobotanical Leaflets 12: 698-704. 2008
- Journal of Biopesticides 2008 1: 41-46
- Ethanobotanical Leaflets 12: 320-336. 2008
- Entomon 2006 (31)1: 57-60
- Journal Plant Protection
- J. Venom. Anim. Toxins incl. Trop. Dis vol.12 no.3 Botucatu 2006
- Chapter in Animal Reproduction
- http://www.scielo.br/pdf/jvatitd/v12n3/31235.pdf
Invited Lectures
- Invited as Resource Person and Delivered a Special Lectures on “Molecular Basis of Entomological Perspective” at Indian Academy of Sciences, Bengaluru, Indian National Science Academy, New Delhi and The National Academy of Sciences, India, Allahabad’s Science Academies’ Refresher Course On Insect Bio-resources and Human Welfare at Department of Zoology, St. Xavier's College (autonomous), Palayamkottai -627 002, Tamil Nadu, India on 19th August 2018.
- Invited as Resource Person and Delivered a Special Lectures on “Molecular techniques for Entomology Research” at Indian Academy of Sciences, Bengaluru, Indian National Science Academy, New Delhi and The National Academy of Sciences, India, Allahabad’s Science Academies’ Refresher Course On Insect Bio-resources and Human Welfare at Department of Zoology, St. Xavier's College (autonomous), Palayamkottai -627 002, Tamil Nadu, India on 19th August 2018.
- Invited as Guest of honor and Delivered an Keynote address on “Molecular spectrum of globin and related genes: Present and Prospect” Venus International Foundation, at 4th Annual Research Meet-ARM 2018, at Radha Regent, Chennai, India on 11th August 2018.
- Invited as Chief Guest and Delivered an Inaugural address on “Complex Genomics and High Consanguinity” at Zoology Student Association, Department of Zoology, St. Xavier's College (autonomous), Palayamkottai -627 002, Tamil Nadu, India, on July 24, 2018.
- On invitation, delivered a Guest Lecture on "Globin Gene Variants: Co-inheritance and Couples at risk (G2 Vs C2)" at " National Seminar on Genetic Diseases with Emphasis on Thalassemia" held on January 8th 2018 at Department of Biotechnology, Malankara Catholic College, Mariagiri, Kaliakkavilai, Tamil Nadu, India.
- Delivered a Keynote address on “Phenomics of interacting globin gene variants in Saudi population” at Human and animal welfare (ZooCong-2018), organized by Department of Zoology, St. Xavier's College (autonomous), Palayamkottai -627 002, Tamil Nadu, India, on January 10-13, 2018.
- Invited as Chairperson to chair the session BIOTECHNOLOGY and IPM in BIOPESTICIDES INTERNATIONAL CONFERENCE (BIOCICON-2009), organized by Crop Protection Research Centre, St. Xavier's College (autonomous), Palayamkottai -627 002, Tamil Nadu, India, on November 26-28, 2009.
At Rialto Bridge: This is the oldest and most famous bridge in Venice, Italy
At University of Zurich
Publications
- 2012
- Sahayaraj, K., Borgio, J. F. and Muthu Kumar, S. 2012. First Record of Aspergillus flavus as a fungal pathogen of the predator Rhynocoris marginatus (Hemiptera: Reduviidae). EntomoBrasilis 5 (1): 80-81.
- Sahayaraj, K. and Borgio, J. F. 2012. Screeing of some mycoinsecticides for managing hairy caterpillar Pericallia ricini in castor. Journal of Entomology. In Press. DOI: 10.3923/je.2012.
- 2011
- Borgio, J.F. 2011. Immobilization of Microbial (Wild and Mutant Strains) Amylase on Coconut Fiber and Alginate Matrix for Enhanced Activity, American Journal of Biochemistry and Molecular Biology, 1(3): 255-264. DOI: 10.3923/ajbmb.2011.255.264
- Upadhyay, SK., Chandrashekar, K., Thakur, N., Verma, PC., Borgio, JF., Singh, PK. and Tuli, R. 2011. RNA interference for the control of whiteflies (Bemisia tabaci) by oral route, Journal of Biosciences, 36(1), 153–161. DOI 10.1007/s12038-011-9009-1. PMID:21451256
- Borgio, J.F., Bency, B.J., Pravin K. Thorat and Archana D. Lonkar. 2011. Gynandropsis pentaphylla DC Extracts on the Production of Microbial Proteins, American Journal of Drug Discovery and Development , 1(2): 129 - 136. DOI: 10.3923/ajdd.2011.129.136
- Borgio JF and Bency BJ. 2011. Production and quality control of entomopathogenic fungal pathogens – a review, esearch & Reviews: A Journal of Microbiology & Virology, 1(1): 5-18.
- 2010
- Borgio, J. F., 2010. RNAi mediated gene knockdown in sucking and chewing insect pests, Journal of Biopesticides, 3(1 special issue): 386 - 393.
- Sahayaraj, K. and Borgio, J. F. 2010. Virulence of entomopathogenic fungus Metarhizium anisopliae (Metsch.) Sorokin on seven insect pests. Indian Journal of Agricultural Research, 44 (3).
- Borgio, J.F. 2010. Is the failure of expression of recombinant protein due to qiRNA?. Chronicles of Young Scientists, 1(2): 1.
- 2009
- Borgio, J. F., 2009. RNA interference (RNAi) technology: a promising tool for medicinal plant research, Journal of Medicinal Plants Research, 3(13): 1176-1183.
- Borgio, J. F., Bency, B.J., Ramesh, S. and Amuthan, M. 2009. Exopolysaccharide production by Bacillus subtilis NCIM 2063, Pseudomonas aeruginosa NCIM 2862 and Streptococcus mutans MTCC 1943 using batch culture in different media. African Journal of Biotechnology, 8(20): 5454-5457.
- * Sahayaraj, K. and Borgio, J. F. 2009. Distribution of Metarhizium anisopliae (Metsch.) Sorokin (Deuteromycotina: Hyphomycetes) in Tamil Nadu, India, its biocontrol potential on Dysdercus cingulatus (Fab.) (Hemiptera: Pyrrhocoridae) Archives of Pthytopathology and Plant Protection, 42(5): 424 – 435. DOI: 10.1080/03235400601160065
- Sahayaraj, K., Borgio, J. F. and Raju, G. 2009. Antifungal activity of three plant extracts on causative agents of groundnut early leaf spot and rust diseases. Journal of Plant Protection Research 49 (1): 53 – 56.
- J. Francis Borgio, Pravin K. Thorat, Archana D. Lonkar: Antimycotic and Antibacterial activities of Gynandropsis pentaphylla DC extracts and its Phytochemical Studies. The Internet Journal of Microbiology. 2008. Volume 5 Number 2.
- 2008
- Borgio, J.F., Bency, B.J. and Neha, S. 2008. Compatibility of Metarhizium anisopliae (Metsch.) Sorok. with Ocimum sanctum Linn. (Tulsi) (Lamiaceae) Extracts Ethnobotanical Leaflets 12: 698-704.
- Sahayaraj, K. and Borgio, J. F. 2008. Tri-tropic interaction of cotton, red cotton bug and green muscardine fungi under in-vito condition. Journal of Biopesticides, 1(1): 41-46.
- Borgio, J.F., Pravin, K.T. and Archana, D.L. 2008. Toxicity of Gynandropsis pentaphylla DC extracts against microbials and its phytochemical profile. Ethnobotanical Leaflets, 12: 320-336. www.siu.edu/~ebl/leaflets/borgio.htm.
- Sahayaraj, K., Raju, G. and Borgio, J. F. 2006. Space, prey feed modulation, reduviid predator and its prey density on the reproductive potential of Acanthaspis pedestris Stal (Insecta: Heteroptera: Reduviidae). In: Perspective in animal ecology and reproduction (Volume 3) (V.K. Gupta and Anil K. Verma eds.), Daya Publishing House, New Delhi pp. 289-309.
- Borgio, J. F. and K. Sahayaraj. 2007. “Bioefficacy of the entomopathogenic fungus, Metarhizium anisopliae (Metsch.) Sorokin (Deuteromycotina: Hyphomycetes) on Dysdercus cingulatus (Fb.) eggs.” Proceedings of the National Seminar on Technology and Management of Bioresearches. Eds. M. Narayann, T.Sethuramalingam, K. Sahayaraj. 29–34.
- Sahayaraj, K., Raja, K. R., Borgio, J. F. 2006. Fungicidal activity of three plant extracts on cowpea wilt pathogen, Fusarium oxysporum f. sp. ciceris. Journal of Plant Protection Research 46 (4): 335 – 338.
- Sahayaraj, K., Joe Alakiaraj, R and Borgio, J. F. 2006. Ovicidal and oviposotional effect of Pedalium murex Linn (Pedaliaceae) root on Dysdercus cingulatus (Fab.) (Hemiptera: Pyrrhocoridae). Entomon. 31(1): 57-60.
- Sahayaraj, K., and Borgio, J. F., Muthu Kumar, S and Prem Anandh, G. 2006. “Antimicrobial activity of Rhynocoris marginatus (Fab) and Catamirus brevipennis (Servile) (Hemiptera: Reduviidae) venom on selected human pathogens.” The Journal of Venomous Animals and Toxins Including Tropical Diseaes 12(3): 487-496.
Trainings in Modern Biology
Workshop on Next Generation sequencing (NGS)-Bioinformatics and Data Analysis (2014) held at AU-KBC Research Centre, MIT, Anna University Chennai, Chennai on 15th to 19th July 2014.
Hands on training on Operator training for Illumina HiSeq 2000 Whole Genome Sequencer on 8 to 10th June 2013, at PMRCS, University of Dammam, Dammam, KSA.
Hands on training on Operator training for Illumina MiSeq Personal Sequencer on 27 to 29th May 2013, at PMRCS, University of Dammam, Dammam, KSA.
Workshop on "Before the start of clinical research on human in KSA" organized by Deanship of Scientific Research, University of Dammam, Dammam, KSA on 22nd April 2013.
Hands on training on Operator training for Illumina MiSeq Personal Sequencer on 12 and 13th February 2013, at PMRCS, University of Dammam, Dammam, KSA.
Hands on raining on In-House Basic Operator training for BDFACS CalibourTM Flow Cytometer on 07-09thJanuary 2013, at PMRCS, University of Dammam, Dammam, KSA.
Hands on raining on Operator training for ABI 3500 Genetic Analyzer on 29th November 2012, at PMRCS, University of Dammam, Dammam, KSA.
Workshop on fungal biotechnology at “Centre for advanced studies in Botany”, Madras University, Chennai. From 7th July to 11th July 2005.
Workshop on Microbial Biotechnology at Bangalore University, Bangalore. From 16th –20th Feb 2009.
National seminar “Proteomics: Advances, Applications and Challenges (PRAAC)” to be held from 19th-20th February 2010, organized by Institute of Bioinformatics and Applied Biotechnology (IBAB), Bangalore.
Papers presented
- J. Francis Borgio. Globin Gene Variants: Co-inheritance and Couples at risk (G2 Vs C2)" at " National Seminar on Genetic Diseases with Emphasis on Thalassemia" held on January 8th 2018 at Department of Biotechnology, Malankara Catholic College, Mariagiri, Kaliakkavilai, Tamil Nadu, India.
- J. Francis Borgio, Sayed AbdulAzeez, Zaki A. Naserullah, Sana Al-Jarrash, Mohammed S. Al-Madan, Ahmed M. Al-Suliman, Mohammed A. AlKhalifah, Huda I. ElFakharay, Amein K. Al-Ali “Phenomics of interacting globin gene variants in Saudi population” at Human and animal welfare (ZooCong-2018), organized by Department of Zoology, St. Xavier's College (autonomous), Palayamkottai -627 002, Tamil Nadu, India, on January 10-13, 2018.
- Sumayh A. Aldakeel, Neda Z. Ghanem, Amani M. Al-Amodi, Lubna Ibrahim Al Asoom, Noor B Almandil, Zaki A. Naserullah, Sana Al-Jarrash, Sayed AbdulAzeez, J. Francis Borgio. Six Newly Identified Variants in Beta-Globin Gene. 8TH Annual Forum for Medical Research at King Abdullah International Medical Research Center, Riyadh, KSA. On 5th to 7th Dec 2017. Page No: 116.
- Fatimah Alkhalifah, Noor B Almandil, Zaki A. Naserullah, Sana Al-Jarrash, Sayed AbdulAzeez, J. Francis Borgio. The -α3.7 deletion is associated with reduced level of hemoglobin (HbA) in healthy females. 8TH Annual Forum for Medical Research at King Abdullah International Medical Research Center, Riyadh, KSA. On 5th to 7th Dec 2017. Page No: 78.
- Amani M. Al-Amodi, Neda Z. Ghanem, Sumayh A. Aldakeel, Lubna Ibrahim Al Asoom, Noor B Almandil, Zaki A. Naserullah, Sana Al-Jarrash, Sayed AbdulAzeez, J. Francis Borgio. Is Hemoglobin A2 (HbA2) a diagnostic parameter for βeta-thalassemia trait (β-TT) in the Saudi population?. 8TH Annual Forum for Medical Research at King Abdullah International Medical Research Center, Riyadh, KSA. On 5th to 7th Dec 2017. Page No: 67.
- Batool Abdulhadi Alkhalifah, Fatimah Abduljalil Alkhalifah, Fatimah Hassan Alajwad, Zaki A. Naserullah, Sana Al-Jarrash, Ahmed M. Al-Suliman, Mohammed S. Al-Madan, Sayed AbdulAzeez, Borgio JF. Sequence variants in the AHSP (α-Hemoglobin stabilizing protein) gene is associated with the level of haematological parameters in Saudis. KAIMRC-ER 5TH Research Day at King Saud bin Abdulaziz University for Health Sciences, Al-Ahsa. On 4th May 2017.
- Mousa A. Alaithan, AbdulAzeez S, Borgio JF. A comprehensive review on the prevalence of beta-globin variations in Saudi Arabia. 2nd International SSMG Symposium, KACST in Riyadh on 26-27th April 2017.
- Lina Ali Alhumaid, AbdulAzeez S, Naserullah ZA, Al-Jarrash S, Borgio JF. HBA1 Gene Mutations of Beta-Thalassemia Patients. The Health Profession Conference 2017. Held at King Saud bin Abdulaziz University for Health Sciences in Riyadh on 23-25th April 2017.
- Al Shammari M, Al Ali R, Al-Balawi N, Al-Enazi M, Al-Muraikhi A, Busaleh F, Al-Sahwan A, Borgio JF, Abdul Azeez S, Al-Ali A, Acharya S. KCNQI Gene Polymorphism and its Association with CVD and T2DM in the Saudi Population. The International Genomic Medicine Conference (3rd IGMC, 2015), Jeddah, Saudi Arabia. From 30th Nov to 3rd Dec 2015.
- Khajehkarimoddini, L. and Borgio J.F. Effect of heat and cold shock on gene expression of Escherichia coli NCIM 2064. In: GeneCity Laboratories. In: 50th Annual Conference of Association of Microbiologists of India (AMI) 2009, organized by National chemical Laboratory, Pune, India, December 15-18, 2009.
- Borgio, J.F. RNAi mediated gene knockdown in sucking and chewing insect pests. In: Biopesticides International Conference (BIOCICON-2009), organized by Crop Protection Research Centre, Department of Advanced Zoology and Biotechnology, St. Xavier's College (autonomous), Palayamkottai -627 002, Tamil Nadu, India, on November 26-28, 2009.
- Borgio, J. F. and Sreekanth,K.B. Gynandropsis pentaphylla DC extracts on the production of microbial proteins. In: National Seminar on Morden Biology - Prespective and prospects, Kristu Jayanti College, Bangalore - 77, India, 19th and 20th March 2009.
- Borgio, J. F. and S. Farheen. Immobilization of microbial (wild and mutant) strains producing apha enzyme, on coconut fibre and alginate matrix, for enhanced activity. In: National Seminar on Morden Biology - Prespective and prospects, Kristu Jayanti College, Bangalore - 77, India, 19th and 20th March 2009.
- Subathra, M., Borgio, J. F. Ramarethinam, S., Murugasen, N. V. and Ramarimuthu, S. Effect of foliar sprayed diazotrophs on the metabolic growth of Black gram Vigna mungo L. In: International Conference on Recent Advances in Biosciences, PGP College, Namakkal, India, 12to13.02.2004.
- Subathra, M., Borgio, J. F., Ramesh, S., Ramarethinam, S., Murugasen, N. V. and Ramarimuthu, S. Synergistic effect of phosphobacteria, VAM and rock phosphate on the morphometric changes in Black gram Vigna mungo L.” In: Symposium on Recent Trends in Biosciences, Sri Paramakalyani College, Alwarkurichi, India, 27to28.02.2004.
- Ebency. I. L, Borgio, J. F., Amuthan, M and Ramesh, S Microbial and biochemical analysis of shrimp and processing environment” In: Symposium on Recent Trends in Biosciences conducted at Sri Paramakalyani College, Alwarkurichi, Tamil Nadu, India. Ibid.
- Ramesh, M., Borgio, J. F., Amuthan, M. “Impact analysis of atrazine on the phosphatase activity and biodegradation potentials of the native phosphate solubilizing bacteria” In: Symposium on Recent Trends in Biosciences, SPK.College, Alwarkurichi, India. Ibid.
- Borgio, J. F., Murugan, P., Ramesh, S. and Amuthan, M. “Optimization of exopolymer production by Pseudomonas aeroginosa NCIM 2862 in the National Seminor on Biodegradation and Bioremediation, Saurahstra College, Madurai, India. 17to18.02.2005.
- Borgio, J. F and K. Sahayaraj “ Bioefficacy of the entomopathogenic fungus, Metarhizium anisopliae on Dysdercus cingulatus eggs.” In: National Seminar on Technology and Management of Bioresearches, St. Xavier’s College, Palayamkottai, India. 21to22.03.2005.
At The Altar of the Fatherland, Rome, Italy
Hands on Experience
- Next Generation sequencing (NGS)-Bioinformatics and Data Analysis
- Illumina HiSeq 2000 Whole Genome Sequencer
- ABI 3500 Genetic Analyzer
- PCR Techniques: Thermal Cycler design, General PCR, RT-PCR, Nested PCR, DNA fingerprinting by RAPD and RFLP – PCR, AGE.
- Immunology: Isolation of IgG, Antigen-Antibody interaction, Radial Immunodiffusion, Immuno-electrophoresis, Ouchterlony double diffusion, Rocket Immuno-electrophoresis, Counter courrent electrophoresis, Dot ELISA.
- Recombinant DNA Technology: Isolation of genomic DNA and Plasmid from bacteria, Quantification of DNA, Restriction digestion and Ligation of DNA, Southern hybridization, Electro-elution of DNA, Gene cloning in bacteria.
- Molecular Biology: Extraction of DNA, Melting point of DNA, Extraction of RNA, Isolation of proteins, SDS-PAGE, Western hybridization.
- Biochemistry: Buffers preparation, Estimation of proteins, Nucleic acids (RNA and DNA), Carbohydrates, fats/ lipids, Amino Acids, Enzyme Assay.
- Microbiology: Bacterial Transformation, Bacterial conjugation, Isolation and maintenance of bacteria and fungi, identification of microorganisms, Antibiotic sensitivity assay, MIC determination.
- Enzyme Technology: Enzyme activity curve, Enzyme activity against time, Enzyme extraction, Enzyme precipitation, Enzyme kinetics – Effect of pH, Temperature and Substrate concentration on enzyme activity, Enzyme immobilization.
- Bio-fertilizer and Bio-pesticide technology: Isolatoin and Identification of Biofertilizers and Biopesticidal organisms, Mass production, Formulation of the product, Degradation of pesticides, Determination of LC50 for common pesticide and Biopesticides.
- Instrumentation: PCR Machine, Gel documentation, Inverted Microscope and Image Processing, Micro and Finppettes, pH meter and pH pen, Diigtal Autoclave, Safety Cabinets, Coolong and Ultra Centrifuge, UV-Vis Spectrophotometer, Electrophoretic and Blotting apparatus for immuno and molecular studies.
Thesis guidance and supervision
- As PhD Thesis Co-Supervisor: Dr Norah Fahad Alhur. Detection of Genetic Disorders Using Human Fetal Cell Free DNA (cffDNA) in The Kingdom of Saudi Arabia. King Saud University, Riyadh, Saudi Arabia. Awarded on 17 May 2022.
- Sahar Solgi, March 2008. Restriction digestion profile of DNA isolated from Agrobacterium tumefaciens NCIM 2145 and Escherichia coli NCIM 2064, Bharati Vidya Peeth University, Pune., In: GeneCity Laboratories Pvt. Ltd., Pune.
- Laleh Khajehkarimoddini, March 2008. Effect of heat and cold shock on gene expression of Escherichia coli NCIM 2064, Bacillus subtilis NCIM 2010 and Staphylococcus aureus isolate, Bharati Vidya Peeth University, Pune., In: GeneCity Laboratories Pvt. Ltd., Pune.
- Shah Dimpy Gautham. May 2008. Effect of mutagens on melting temperature of DNA of Bacillus subtilis NCIM 2010. Suryadatta Group of Institutes of Management and information Technology (SCMIT), Pune. In: GeneCity Laboratories Pvt. Ltd., Pune.
- Sonali Satpathy, April 2008. Variability in response to uv-b mutation among strains of Azotobacter chrococcum and Metarhizium anisopliae revealed by RAPD analysis and their antimicrobial susceptibility, Tm and growth requirements, Allahabad Agricultural Institute – Deemed University, Allahabad (U.P), In: GeneCity Laboratories Pvt. Ltd., Pune.
- Shio Prakash Yadav, April 2008. RAPD, antimicrobial sensitivity profile, growth requirements and Tm pattern of UV mutated Metarhizium anisopliae and Azotobacter chrococcum, Allahabad Agricultural Institute – Deemed University, Allahabad (U.P), In: GeneCity Laboratories Pvt. Ltd., Pune.
- Niharika Jaiswal, March 2008. Strain improvement of Xanthomonas compestris for Xanthan gum production by Acridine dye, Allahabad Agricultural Institute – Deemed University, Allahabad (U.P), In: GeneCity Laboratories Pvt. Ltd., Pune.
- Vineet Kumar, March 2008. Screening of best agrowaste media for xanthan production by Xanthomonas campestris NCIM 2954, Rai Foundation College, Raipur, Chhattisgarh. In: GeneCity Laboratories Pvt. Ltd., Pune.
- Neha Sharma, March 2008. Side effects of certain bio and chemical pesticides on entomopathogenic fungi, Metarhizium anisopliae NCIM 1311 (Deuteromycotina: Hyphomycetes), Rai Foundation College, Raipur, Chhattisgarh. In: GeneCity Laboratories Pvt. Ltd., Pune.
- Naveen Kumar, March 2008. Effect of acridine orange and UV on Escherichia coli and Staphylococcus aureus, their antibiotic sensitivity and RAPD profile, Rai Foundation College, Raipur, Chhattisgarh. In: GeneCity Laboratories Pvt. Ltd., Pune.
- Upendra Kumar Singh, March 2008. Screening of low cost media for xanthan production by Xanthomonas campestris NCIM 2954, Allahabad Agricultural Institute – Deemed University, Allahabad (U.P), GeneCity Laboratories Pvt. Ltd., Pune.
- Krishna Kumar Mishra, March 2008 Effect of mutagen, acridine orange on DNA melting patter of Azotobacter chrococcum, Allahabad Agricultural Institute – Deemed University, Allahabad (U.P), : GeneCity Laboratories Pvt. Ltd., Pune.
- Sharad Pratap Singh, March 2008. Effect of mutagen, dimethoate on DNA melting patter of Azotobacter chrococcum, Allahabad Agricultural Institute – Deemed University, Allahabad (U.P), : GeneCity Laboratories Pvt. Ltd., Pune.
- Akash Patel, March 2008. Synergistics of entomopathogenic fungi Metarhizium anisopliae NCIM 1311 (Deuteromycotina: Hyphomycetes) with certain chemical pesticides, Rai Foundation College, Raipur, Chhattisgarh. In: GeneCity Laboratories Pvt. Ltd., Pune.
- Chitesh Rangari, March 2008. RAPD-PCR profile of chloropyrifos mutated Azotobacter strains and the antibiotic sensitivity pattern, Rai Foundation College, Raipur, Chhattisgarh. In: GeneCity Laboratories Pvt. Ltd., Pune.
- Abhishek Gupta, March 2008. Establishment and characterization of antibiotic sensitivity profile of Azotobacter isolates and DNA damaged induced by mutagen, endosulfan, Rai Foundation College, Raipur, Chhattisgarh. In: GeneCity Laboratories Pvt. Ltd., Pune.
- Elham Jafarzadeh. Feb. 2008. Studies on UV mutated DNA from Escherichia coli and Staphylococcus aureus, Modern College of Arts, Science & Commerce, Pune, In: GeneCity Laboratories Pvt. Ltd., Pune.
- Chandana, C. Jan2008 Xanthan production by Xanthomonas campestris NCIM 2954 using batch culture under different media, Extol Institute of Management, Jahangirabad, Bhopal (M.P.). In: GeneCity Laboratories Pvt. Ltd., Pune.
- Monika, B. Jan2008 RAPD and RFLP profiles of UV mutated DNA from Escherichia coli and Staphylococcus aureus, Extol Institute of Management, Jahangirabad, Bhopal (M.P.). In: GeneCity Laboratories Pvt. Ltd., Pune.
- M. Sc., Hematology; Asma Yousef Alsulaim: 2018-2020. The association between genetic polymorphisms in two coagulation system genes and increase risk of venous thromboembolism in cancer patients in Eastern province of Saudi Arabia, In: Collage of Applied Medical Science, AND Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. (As Co- Supervisor)
- M. Sc., Microbiology: Ms Mariam Ali AlSayed: 2021-2022. Application of bacterial proteases in the biological treatment of some proteinaceous wastes. College of Science, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. (As Co-Supervisor)
- M.Sc., Biotechnology: Ms Hanan Aldossary: 2020-2021. Study of antibiotic resistance genes of Candia auris and the nanoparticles as a potential therapeutic. Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. (As Supervisor).
- M.Sc., Biotechnology: Mr Ayman M. Al-Qaaneh: 2020-2021. Efficacy and Safety of Tocilizumab in COVID-19 patients: A Retrospective Observational Study. Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. (As Supervisor)
- M.Sc., Biotechnology: Ms. Bayan Sonbol: 2021-2022. Identifying Pathogenic Variations on Early Stage of Pregnancy Using Invasive and Non-Invasive Prenatal Samples. Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. (As Supervisor: 2021-2022).
- M.Sc., Biotechnology: Ms Eman Saleh Al-Hasani. 2022-2023. Development of New Drug against Multidrug Resistance Candida auris by Mining Genome from Marine Bacteria. Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. (As Co-Supervisor: 2021-2022 ).